diff --git a/CHANGELOG.md b/CHANGELOG.md
index f1146591..c160a876 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -15,7 +15,7 @@ The format is based on [Keep a Changelog](https://keepachangelog.com/en/1.0.0/).
 - Filter users by actor type: Person, Bot or Application
 - Add ability to configure Media Preview Proxy, User Backup, Websocket based federation and Pleroma.Web.Endpoint.MetricsExporter settings
 - Mobile and Tablet UI for Single Report show page
-
+- Ability to set rules and conditions for rendering settings (e.g. `:proxy_remote` setting is hidden if `:uploader` setting is set to `Pleroma.Uploaders.Local`)
 ### Changed
 
 - **Breaking**: AdminAPI changed User field `confirmation_pending` to `is_confirmed`
diff --git a/src/views/settings/components/Setting.vue b/src/views/settings/components/Setting.vue
index 7593fb3d..28080b21 100644
--- a/src/views/settings/components/Setting.vue
+++ b/src/views/settings/components/Setting.vue
@@ -7,6 +7,7 @@
     <div v-if="settingGroup.key === 'Pleroma.Emails.Mailer'">
       <div v-for="setting in settingGroup.children.filter(setting => !setting.group)" :key="setting.key">
         <inputs
+          v-if="followsRules(setting.key, settingGroup.key, state)"
           :setting-group="settingGroup"
           :setting="setting"
           :data="data"/>
@@ -15,6 +16,7 @@
         v-for="setting in emailAdapterChildren"
         :key="setting.key">
         <inputs
+          v-if="followsRules(setting.key, settingGroup.key, state)"
           :setting-group="settingGroup"
           :setting="setting"
           :data="data"/>
@@ -24,6 +26,7 @@
       <div v-for="setting in settingGroup.children" :key="setting.key">
         <div v-if="!compound(setting)">
           <inputs
+            v-if="followsRules(setting.key, settingGroup.key, state)"
             :setting-group="settingGroup"
             :setting="setting"
             :data="data"
@@ -33,6 +36,7 @@
           <el-divider v-if="divideSetting(setting.key)" class="divider"/>
           <div v-if="!setting.children">
             <inputs
+              v-if="followsRules(setting.key, settingGroup.key, state)"
               :setting-group="settingGroup"
               :setting="setting"
               :data="data[setting.key]"
@@ -73,6 +77,7 @@ import Inputs from './Inputs'
 import i18n from '@/lang'
 import _ from 'lodash'
 import marked from 'marked'
+import { settingFollowsRules } from '../rules'
 
 export default {
   name: 'Setting',
@@ -109,6 +114,9 @@ export default {
     },
     loading() {
       return this.$store.state.settings.loading
+    },
+    state() {
+      return this.$store.state.settings.settings
     }
   },
   methods: {
@@ -127,6 +135,9 @@ export default {
     divideSetting(key) {
       return [':sslopts', ':tlsopts', ':adapter', ':poll_limits', ':queues', ':styling', ':invalidation', ':multi_factor_authentication'].includes(key)
     },
+    followsRules(setting, settingGroup, state) {
+      return settingFollowsRules(setting, settingGroup, state)
+    },
     getFormattedDescription(desc) {
       return marked(desc)
     },
diff --git a/src/views/settings/rules.js b/src/views/settings/rules.js
new file mode 100644
index 00000000..c791818d
--- /dev/null
+++ b/src/views/settings/rules.js
@@ -0,0 +1,26 @@
+const rules = [{
+  name: 'renderIfNotEqual',
+  key: ':proxy_remote',
+  groupKey: 'Pleroma.Upload',
+  group: ':pleroma',
+  targetKey: ':uploader',
+  targetGroup: 'Pleroma.Upload',
+  notEqual: 'Pleroma.Uploaders.Local'
+}]
+
+const renderIfNotEqual = (state, { group, groupKey, targetKey, notEqual }) => {
+  return state[group][groupKey][targetKey] !== notEqual
+}
+
+const rulesMap = {
+  renderIfNotEqual
+}
+
+export const settingFollowsRules = (settingKey, settingGroupKey, state) => {
+  const rule = rules.find(rule => rule.groupKey === settingGroupKey && rule.key === settingKey)
+  if (!rule) return true
+
+  const ruleFn = rulesMap[rule.name]
+  if (!ruleFn) return true
+  return ruleFn(state, rule)
+}
diff --git a/test/views/settings/settingFollowsRules.test.js b/test/views/settings/settingFollowsRules.test.js
new file mode 100644
index 00000000..a67745c2
--- /dev/null
+++ b/test/views/settings/settingFollowsRules.test.js
@@ -0,0 +1,35 @@
+import { settingFollowsRules } from '@/views/settings/rules'
+
+describe('Check if settings follow rules', () => {
+  it('does not render :proxy_remote when local :uploader is selected', () => {
+    const state = { ':pleroma': { 'Pleroma.Upload': { ':uploader': 'Pleroma.Uploaders.Local' }}}
+
+    expect(settingFollowsRules(':proxy_remote', 'Pleroma.Upload', state)).toBeFalsy()
+  })
+
+  it('render :proxy_remote when local :uploader is not selected', () => {
+    const state = { ':pleroma': { 'Pleroma.Upload': { ':uploader': 'Pleroma.Uploaders.S3' }}}
+
+    expect(settingFollowsRules(':proxy_remote', 'Pleroma.Upload', state)).toBeTruthy()
+  })
+
+  it('render setting when there is no rule', () => {
+    const state = { ':pleroma': { 'Pleroma.Upload': { ':uploader': 'Pleroma.Uploaders.Local' }}}
+
+    expect(settingFollowsRules(':filters', 'Pleroma.Upload', state)).toBeTruthy()
+  })
+
+  it('render setting when one of the keys is undefined', () => {
+    const state = { ':pleroma': {}}
+
+    expect(settingFollowsRules(':level', undefined, state)).toBeTruthy()
+
+    expect(settingFollowsRules(':admin_token', undefined, state)).toBeTruthy()
+  })
+
+  it('render setting when state is empty', () => {
+    const state = { ':pleroma': { 'Pleroma.Upload': {}}}
+
+    expect(settingFollowsRules(':proxy_remote', 'Pleroma.Upload', state)).toBeTruthy()
+  })
+})
\ No newline at end of file